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Patients with known allergy to the cephalosporin group of antibiotics. Keflex is a semi-synthetic cephalosporin antibiotic for oral administration. Side effects are commonly associated with taking Keflex and other antibiotics, although some side effects can be serious. Side effects of Cephalexin. Medications with known interactions with Keflex include blood thinners, probenecid, and Metformin. Side effects can be serious. Stopping the medication too early may allow bacteria to continue to grow resulting in a relapse of the infection.
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